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我们于1992年1月～1993年12月用扑尔敏治疗小儿哮喘性支气管炎及毛细支气管炎43例,取得较好疗效,报告如下.1 资料与方法1.1 对象 76例患儿诊断标准按最新儿童哮喘诊断标准.多有湿疹及其它过敏史,有呼气性呼吸困难,肺部有哮鸣音等类似哮喘症状,有发热、血白细胞增高等感染表现.随机分成观察组和对照组.观察组43例,其中男29例,女14例;年龄2个月～6个月14例,～1岁10例,～2岁3例,～3岁7例,～5岁3例.～8岁6例;对照组33例,男22例,女11例;年龄2个月～6个月17例,～1岁9例,～2岁2例,～3岁2例,～5岁2例,～8岁1例.1.2 入院前病程 观察组入院时平均病程((?)±S)为24.5士1.02天,对照组平均病程为2.91士1.33天,无显著性差异(t=1.51,P>0.05).1.3 方法 两组同时应用抗炎、止咳、解痉等药物,均用常规剂量.观察组加用扑尔敏片0.35mg/(kg·d),每日3次口服,哮鸣音消失后停药.
We in January 1992 ~ December 1993 chlorpheniramine treatment of pediatric asthmatic bronchiolitis and bronchiolitis in 43 cases, and achieved good results, the report is as follows.1 Materials and Methods 1.1 Object The diagnostic criteria of 76 children according to the latest Childhood asthma diagnostic criteria.Many eczema and other allergic history, with expiratory breathing difficulties, wheezing and other lung symptoms such as asthma, fever, leukocytosis and other infections were randomly divided into observation group and control group.Observation There were 43 males and 14 females, including 14 males and females aged from 2 months to 6 months, 10 cases of ~ 1 year old, 3 cases of ~ 2 years old, 7 cases of ~ 3 years old and 3 cases of ~ 5 years old. Year-old in 6 cases; control group of 33 cases, 22 males and 11 females; age 2 months to 6 months in 17 cases, ~ 1 year old in 9 cases, 2 years old in 2 cases, 3 years old in 2 cases, ~ 5 years old 2 Cases, ~ 8 years old in 1 case .1.2 Pre-admission course of observation group average duration of admission (±?) Was 24.5 disabilities 1.02 days, the average duration of the control group was 2.91 ± 1.33 days, no significant difference (t = 1.51, P> 0.05) .1.3 Methods The two groups were given anti-inflammatory, cough, antispasmodic and other drugs at the same time, the conventional dose were used. The observation group plus chlorpheniramine 0.35mg / (kg · d), 3 times a day orally, After the song disappears.