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目的探讨原发性肝癌自发性破裂的危险因素。方法将1999年1月—2008年12月间收治的原发性肝癌自发性破裂的31例患者(破裂组)与同期住院的未发生破裂的肝癌患者中随机抽出的31例患者(对照组)进行临床资料的回顾分析与对比。结果单因素及多因素分析显示,与原发性肝癌自发性破裂有关的有因素有3个,即APTT,HBeAg,肿瘤突出肝表面的最大突出高度。结论APTT,HBeAg及肿瘤突出肝表面的最大高度是肝癌自发性破裂的独立危险因素。
Objective To explore the risk factors of spontaneous rupture of primary liver cancer. Methods Thirty-one patients (control group) randomly selected from 31 patients (rupture group) with spontaneous rupture of primary liver cancer who were treated between January 1999 and December 2008 and those without rupture who were hospitalized in the same period, Clinical data review and analysis. Results Univariate and multivariate analysis showed that there were three factors related to spontaneous rupture of primary hepatocellular carcinoma, namely, APTT, HBeAg, and the maximum prominent height of tumor-protruding liver surface. Conclusion The maximum height of APTT, HBeAg and tumor protruding liver surface are independent risk factors of spontaneous rupture of liver cancer.