我院自1985年至1996年对52例病期短、病变范围小、X线片上显示在4.5cm以下的骨巨细胞瘤,在手术刮除术后,植骨前用95％酒精灭活的方法进行治疗,结果疗效满意。复发率由以前未用灭活时的34％～50％降低到目前的19.2％,认为手术过程中的灭活是防治复发的关键。现详细报告如下。 1 临床资料 本组病例52例。股骨下端27例,胫骨上端22例,桡骨下端3例。年龄15～26岁,其中男性45例,女性7例。左侧15例,右侧37例。大多数病例早期有间歇性隐痛,逐渐肿胀,压痛,拍片后通常表现为有溶骨性破坏,呈扁心、皂泡样,骨皮质变薄似 In our hospital from 1985 to 1996, 52 cases of giant cell tumors of bone with a short period of disease, a small lesion size, and an X-ray size of less than 4.5 cm were inactivated with 95% alcohol before bone grafting. Methods for treatment, the results were satisfactory. The recurrence rate was reduced from 34% to 50% when not previously inactivated to 19.2% at present, and it is considered that the inactivation during the operation is the key to prevent recurrence. The detailed report is as follows. 1 Clinical data 52 patients in this group. Twenty-seven cases were found at the lower end of the femur, 22 at the upper end of the humerus and 3 at the lower end of the humerus. Age 15 to 26 years old, 45 males and 7 females. There are 15 cases on the left side and 37 cases on the right side. In most cases, there are intermittent pains, swelling and tenderness in the early stage. After the film is taken, it usually shows osteolytic destruction, showing flat heart, soap bubble, thin cortical bone.