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目的:观察静脉自控镇痛(patient controlled intravenous analgesia,PCIA)在晚期癌痛病人应用中的临床效果。方法:选择晚期癌痛病人56例,采用PCIA连续输注。镇痛配方:枸橼酸舒芬太尼注射液200ug、地佐辛注射液10mg、盐酸托烷司琼注射液10mg、咪达唑仑注射液10mg、地塞米松注射液10mg用生理盐水稀释至100ml观察镇痛效果、睡眠质量、恶心、呕吐、便秘等副作用。结果有效镇痛率98.21﹪,病人生活质量和睡眠质量明显提高,以前口服或肌注阿片类药物引起的恶心、呕吐、便秘等得到改善。结论静脉自控镇痛可持续有效控制晚期癌痛,提高患者的生存质量。
Objective: To observe the clinical effect of patient controlled intravenous analgesia (PCIA) in patients with advanced cancer pain. Methods: 56 patients with advanced cancer pain were selected and continuously infused by PCIA. Analgesic formula: sufentanil citrate injection 200ug, dezocine injection 10mg, tropisetron hydrochloride injection 10mg, midazolam injection 10mg, dexamethasone injection 10mg diluted with saline to 100ml observed analgesic effect, sleep quality, nausea, vomiting, constipation and other side effects. Results The effective analgesic rate was 98.21%. The quality of life and sleep quality of patients were significantly improved. Nausea, vomiting and constipation caused by oral or intramuscular opioids were improved. Conclusion Intravenous controlled analgesia can effectively and effectively control advanced cancer pain and improve the quality of life of patients.