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强化降压对估算的肾小球滤过率(estimated glomerular filtration rate,eGFR)正常的脑血管病患者肾功能的影响尚不确定。方法和结果:纳入重复测定血肌酐的2610例研究对象,随机分为较低(<130mm Hg,1 mm Hg=0.133kPa)和较高降压目标(130~149mm Hg)组,分别应用线性混合模型和Logistic回归分析年度eGFR下降及快速下降
The effect of intensive antihypertensive therapy on renal function in patients with normal cerebrovascular disease with an estimated glomerular filtration rate (eGFR) is uncertain. Methods and Results: A total of 2610 study subjects were enrolled in the study. Serum creatinine was randomly divided into two groups: lower (<130mm Hg, 1 mm Hg = 0.133kPa) and higher decompression target (130-149mm Hg) Models and logistic regression analysis of annual eGFR decline and rapid decline