在小鼠、大鼠、地鼠和沙鼠间实验传播隐匿管状线虫Syphacia ob Velata

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将感染了隐匿管状线虫(Cyphcia obvelata)的小鼠分别与未感染的SD大鼠(Spragne-Dawley rats)、长爪沙鼠和金黄地鼠共同饲养在一个笼子里,这些动物被感染上了隐匿管状线虫。再将这些动物分别移到未感染小鼠的笼中,隐匿管状线虫又从大鼠、沙鼠传给小鼠。这个实验进一步证明了大鼠、地鼠和沙鼠对隐匿管状线虫的易感性。隐匿管状线虫是小鼠中’.s’见的烧虫,偶尔也寄生于大鼠、地鼠和沙鼠。感染隐匿管状线虫一般不致病,但严重的感染使动物不适合于精密的研究,因为营养和血液指标可能不正常。隐匿管状线虫的生活史是直接的。雌虫被宿主摄入后第五天即成熟受精,受孕的雌虫在第十二天从盲肠移行到肛门。虫卵产在肛门周围的皮肤和毛上。潜在期一般为n一15天。传播途径包括:通过笼中动物间的相互舔赶食入了肛门附近的虫卵;食入被含有胚胎的虫卵污染的食物和水,以及回归感染。小鼠的鼠龄和感染率呈负相关,感染率最高是在出生后的4一5周。诊断隐匿管状线虫有几种方法:死后检查结肠和盲肠的内容物;粪便漂浮法,粪便涂片以及肛门周围胶纸粘卵法。后一种方法是诊断活动物隐匿管状线虫最广泛使用的方法。在诊断检查过程中,我们发现有些种烧虫没有寄生在其固有的宿主体内,而是多次发现在其他实验动物中。例如隐匿管状线虫在沙鼠体内,这就引起了我们对几种实验啮齿动物烧虫的潜在宿主范围的注意。这篇文章的目的是报告愉匿管状线虫从小鼠(Musmuseulus)传播到金黄地鼠(Mesoeriee-tus auratus)、长爪沙鼠(Meuomesan君u ieulatus)、大鼠(Rattus,:oaegius),然后再回归到小鼠的传播途径。 Mice infected with Cyphcia obvelata were housed individually with uninfected Spragne-Dawley rats, Meriones unguiculatus, and Hamster in a cage that was infected with an occult Tubular nematode. Then these animals were moved to uninfected mice in the cage, hidden tube-shaped nematodes from rats, gerbils to mice. This experiment further demonstrates the susceptibility of rats, hamsters and gerbils to occluded tubular nematodes. Hidden tubular nematodes are ’.s’ found in mice, and occasionally also parasites in rats, hamsters and gerbils. Tubercular infection with nematodes is generally not pathogenic, but serious infections make animals unsuitable for sophisticated research because of nutritional and blood parameters may not be normal. The history of hiding tubular worms is straightforward. The female was fertilized on the fifth day after being ingested by the host, and the pregnant female migrated from the cecum to the anus on the twelfth day. The egg is produced on the skin and hair around the anus. The potential is usually n a 15 days. Routes of transmission include: feeding the eggs near the anus by licking each other among the animals in the cage; ingesting food and water contaminated with the eggs containing the embryo and returning the infection. Mouse age and infection rate was negatively correlated, the highest infection rate is 4 to 5 weeks after birth. There are several ways to diagnose hiding tubular nematodes: examine the contents of the colon and cecum after death; faecal floatation, stool smear, and adhesive tape pasting around the anus. The latter method is the most widely used method to diagnose tubular worms in live animals. During the diagnostic tests, we found that some species of insects were not parasitic in their native hosts, but were repeatedly found in other laboratory animals. For example, hiding the tubular nematode in the gerbil raises our awareness of the potential host range for several experimental rodent burns. The purpose of this article is to report the discovery of the presence of tubular parasitic nematodes from Musmuseulus to Mesoeriee-tus auratus, Meuomes imulatus, rats (Rattus,: oaegius) and then Return to the route of transmission in mice.
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