60例肢端肥大症进行经蝶骨的垂体显微外科手术治疗,手术前后对垂体功能全面检查与评价。男性33例,女性27例,男性平均年龄46岁,女性平均年龄47岁,诊断依据临床症状体征,生化,x线照相及CT扫描检查等,术前与术后10-14天、6个月、1年进行检查,平均随访期为3.3年(0.5～7.0年)。所有病人的垂体腺瘤切除均通过鼻中隔经蝶骨的手术常规,神经外科医师尽力切除垂体瘤,并保存正常部分,然后局部再给96％乙醇毁坏残余瘤 Sixty cases of acromegaly were treated by transsphenoidal pituitary microsurgery. The pituitary function was examined and evaluated before and after surgery. There were 33 males and 27 females. The average age of males was 46 years and the average age of females was 47 years. The diagnosis was based on clinical signs and symptoms, biochemistry, x-ray and CT scan. Preoperative and postoperative 10-14 days and 6 months , 1 year examination, the average follow-up period was 3.3 years (0.5-7.0 years). All patients with pituitary adenoma resection through the nasal septal transversal surgery routine, neurosurgeons try to remove the pituitary tumor, and save the normal part of the local and then give 96% ethanol to destroy the residual tumor