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[目的]观察小建中颗粒联合匹维溴铵对腹泻型肠易激综合征的治疗效果。[方法]将114例腹泻型肠易激综合征患者随机分为2组,每组57例。治疗组使用小建中颗粒联合匹维溴铵,对照组使用匹维溴铵,疗程均为2周。[结果]治疗后2组患者腹泻次数、腹痛、大便性状均较治疗前有明显改善(P<0.05),2组相比差异无统计学意义(P>0.05);治疗后4周随访,治疗组复发率低,与对照组比较差异有统计学意义(P<0.05)。[结论]小建中颗粒联合匹维溴铵治疗腹泻型肠易激综合征临床疗效满意。
[Objective] To observe the therapeutic effect of Xiaojianzhong granule combined with piroxicam on diarrhea-predominant irritable bowel syndrome. [Methods] 114 patients with diarrhea-predominant irritable bowel syndrome were randomly divided into two groups of 57 cases. The treatment group with small Jianzhong particles combined with pivalopyrine bromide, control group use pinaverium bromide, treatment were 2 weeks. [Results] The number of diarrhea, abdominal pain and stool in two groups were significantly improved after treatment (P <0.05), but there was no significant difference between the two groups (P> 0.05) Group recurrence rate is low, compared with the control group, the difference was statistically significant (P <0.05). [Conclusion] Xiaojianzhong granule combined with piroxicam is satisfactory in the treatment of diarrhea-predominant irritable bowel syndrome.