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目的:探讨α-L-岩藻苷酶(AFU)、γ-谷氨酰转肽酶(GGT)、甲胎蛋白(AFP)三项联合检测对原发性肝癌诊断的临床意义。方法:测定原发性肝癌40例、肝硬化50例、健康体检者50例AFU、GGT、AFP血清含量。结果:原发性肝癌三项指标与肝硬化及正常组比较差异均有统计学意义(P<0.01),对原发性肝癌,AFU、GGT与AFP联合检测阳性率达95.8%。结论:AFU、GGT、AFP三项联合检测可提高肝癌的阳性诊断率。
Objective: To investigate the clinical significance of triple detection of α-L-fucosidase (AFU), γ-glutamyl transpeptidase (GGT) and alpha fetoprotein (AFP) in the diagnosis of primary liver cancer. Methods: The serum levels of AFU, GGT and AFP in 40 cases of primary liver cancer, 50 cases of cirrhosis and 50 cases of healthy subjects were measured. Results: The three indexes of primary liver cancer were significantly different from those of cirrhosis and normal group (P <0.01). The positive rate of combined detection of primary liver cancer, AFU, GGT and AFP was 95.8%. Conclusion: The three joint detection of AFU, GGT and AFP can improve the positive diagnosis rate of liver cancer.