论文部分内容阅读
目的:探讨冠状动脉慢血流(CSF)现象与血清脂蛋白的关系。方法:选择经冠状动脉造影检查证实存在CSF现象,且矫正的心肌梗死溶栓治疗临床试验(TIMI)帧数(CTFC)>27帧48例为观察组;另外选择同期经冠状动脉造影检查显示血流正常48例为对照组。两组均行三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)常规检查,比较两组血脂水平,分析血脂水平与CSF的相关性。结果:两组TG和TC水平比较,差异不显著(P>0.05);观察组LDL-C水平显著高于对照组(P<0.05),HDL-C水平非常显著低于对照组(P<0.01)。观察组HDL-C水平与CTFC帧数呈显著负相关(r=-0.56,P<0.05),LDL-C水平与CTFC帧数呈显著正相关(r=0.68,P<0.05)。结论:HDL-C水平下降及LDL-C水平升高,与CSF发生密切相关。
Objective: To investigate the relationship between coronary blood flow (CSF) and serum lipoprotein. Methods: CSF phenomenon was confirmed by coronary angiography, and 48 cases of corrected myocardial infarction thrombolytic therapy (TIMF)> 27 frames (CTFC)> 48 cases were observed. In addition, the same period by coronary angiography showed that blood 48 cases of normal flow control group. The levels of triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) were routinely examined in both groups. Blood lipid levels Correlation with CSF. Results: The levels of TG and TC in the two groups were not significantly different (P> 0.05). The levels of LDL-C in the observation group were significantly higher than those in the control group (P <0.05), while the levels of HDL-C in the observation group were significantly lower than those in the control group ). The level of HDL-C in the observation group was negatively correlated with the number of CTFC frames (r = -0.56, P <0.05). The LDL-C level was positively correlated with the number of CTFC frames (r = 0.68, P <0.05). Conclusion: The level of HDL-C is decreased and the level of LDL-C is elevated, which is closely related to the occurrence of CSF.