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目的:探讨、分析百令胶囊(CC)对狼疮性肾炎的临床疗效。方法:收治狼疮性肾炎(LN)患者90例,平分为两组。对照组给予西药治疗,治疗组在此基础上给予百令胶囊治疗,比较两组治疗效果。结果:治疗后治疗组总有效率和狼疮活动积分明显高于对照组(P<0.05);与治疗前相比,治疗后两组ANA、抗ds-DNA和抗Sm抗体占总患者百分比明显降低(P<0.05);治疗组治疗后与治疗前相比,HCB、WBC、ALB、C3以及C4明显升高(P<0.05),Scr、TP/24 h、Ig G、ESR以及尿RBC明显降低(P<0.05);与对照组治疗后相比,治疗组治疗后WBC、ALB、C3和C4明显升高(P<0.05),TP/24 h、Ig G以及ESR以及尿RBC明显降低(P<0.05)。结论:在常规治疗的基础上给予百令胶囊治疗狼疮性肾炎临床疗效显著,同时对狼疮活动积分以及相关理化检查指标也具有很好的改善作用。
Objective: To investigate and analyze the clinical effect of Bailing capsule (CC) on lupus nephritis. Methods: 90 patients with lupus nephritis (LN) were divided into two groups. The control group was treated with western medicine. On the basis of this, the treatment group was given Bailing capsule treatment, and the treatment effect was compared between the two groups. Results: After treatment, the total effective rate and the lupus active score in the treatment group were significantly higher than those in the control group (P <0.05). Compared with those before treatment, the percentages of ANA, anti-ds-DNA and anti-Sm antibody in the two groups were significantly decreased (P <0.05). The levels of HCB, WBC, ALB, C3 and C4 were significantly increased (P <0.05), Scr, TP / 24 h, Ig G, ESR and urine RBC were significantly lower (P <0.05). Compared with control group, WBC, ALB, C3 and C4 in treatment group were significantly increased (P <0.05), TP / 24 h, IgG, ESR and urine RBC decreased <0.05). Conclusion: Bailing capsule is effective in treating lupus nephritis on the basis of routine treatment. It also has a good effect on lupus active score and related physical and chemical examination indexes.