论文部分内容阅读
A variety of phenyl alkyl sulfides were oxidized enantioselectively with NaIO_4 in chiralmicellar systems formed from eight chiral surfactants,to give optical active sulfoxides.The enantiomerexcesses ranged from 1.6 to 15.0%.To understand the mechanistic detail of this asymmetric oxi-dation in chiral micelle,the effects of structure both in substrates and surfactants on the optical yieldof the oxidation were studied and discussed.Generally,increasing the alkyl chain length both in sur-factants and in substrates enhances the optical yield,also the surfactant with hydroxy group at itsappropriate position gives better enantioselectivity,suggesting the enzymic characteristics of the chiralmicelle.
A variety of phenyl alkyl sulfides were oxidized enantioselectively with NaIO_4 in chiralmicellar systems formed from eight chiral surfactants, to give optical active sulfoxides. The enantiomerexcesses ranged from 1.6 to 15.0%. To understand the mechanistic detail of this asymmetric oxi- dation in chiral micelle, the effects of structure both in substrates and surfactants on the optical yield of the oxidation were studied and discussed. Normally increasing the alkyl chain length both in sur-factants and in substrates enhances the optical yield, also the surfactant with hydroxy group at its proper position gives better enantioselectivity, suggesting the enzymic characteristics of the chiralmicelle.