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目的：为了探讨缺氧缺血性脑病（ＨＩＥ）量化诊断方法。方法：对正常新生儿３５例，ＨＩＥ１５例，使用Ａｃｕｓｏｎ１２８×Ｐ／１０电脑声像仪，Ｖ７１４扇扩探头及Ｌ７高频线阵探头，经耳郭上方双侧颞侧，直接检测蛛网膜与脑沟及蛛网膜与脑回的间隙，并同时测双侧大脑皮层血流，于日龄１、３、５ｄ连续检测。结果：正常新生儿蛛网膜下腔间隙显示清晰，结构稳定，蛛网膜与脑沟之间的间隙为１９３～２．３３ｍｍ，与脑回之间的间隙１４４～１６４ｍｍ，而１５例ＨＩＥ患儿大脑皮层沟、回结构显示不清，沟、回起伏结构消失，蛛网膜下腔间隙显示不清。动态观察随患儿病情逐渐好转，蛛网膜与脑沟之间的间隙由０７６ｍｍ增至１９１ｍｍ，与脑回之间的间隙由００６ｍｍ增至０２９ｍｍ。结论：测量蛛网膜下腔间隙，方法简便、无创、数据可靠，可作为ＨＩＥ脑水肿量化诊断指标。
Objective: To investigate the quantitative diagnosis of hypoxic-ischemic encephalopathy (HIE). Methods: Thirty-five normal neonates and 15 HIE patients were examined by Acuson128 × P / 10 computer imager, V714 fan probe and L7 high frequency linear probe. The arachnoid and brain Ditch and arachnoid and brain back to the gap, and at the same time measure the bilateral cerebral cortex blood flow, 1,3,5 days of continuous detection. Results: The normal neonatal subarachnoid space showed a clear and stable structure. The gap between the arachnoid and sulci was 193 ~ 2.33mm, and the gap between the back and the brain was 144 ~ 164mm. 15 cases of HIE children cerebral cortex groove, back structure showed unclear, ditch, back and forth disappearance of the structure, subarachnoid space showed unclear. Dynamic observation with the children’s condition gradually improved, the arachnoid and sulci gap increased from 076mm to 191mm, and the gap between the brain back from 0 06mm to 0 29mm. Conclusion: The measurement of subarachnoid space, the method is simple, noninvasive, reliable data, which can be used as quantification of HIE brain edema indicators.