1964年,Demitras 首先合成了这类化合物。到七十年代,Markovskii 和 Middle-ton 才较详细地研究了它在制备有机氟化合物上时应用。这类氟化剂,其特点是:在化学反应上,速度比较快,反应温和,并具有较好的反应选择性,因而消除反应和重排反应少;在技术操作上,比较方便,可在一般的玻璃容器中进行,不需压力,同时对温度的适应范围较大。它易与羟基、羰基反应而实现氟的取代,广泛应用于含氟有机天然产物的合成,如制备 In 1964, Demitras first synthesized these compounds. By the seventies, Markovskii and Middle-ton had only studied in more detail when it was used in the preparation of organofluorine compounds. Such fluorinating agent, which is characterized by: the chemical reaction speed, mild reaction, and has a good reaction selectivity, thus eliminating the reaction and rearrangement reaction less; in technical operation, more convenient, available at General glass containers, without pressure, while the temperature to adapt to a larger range. It is easy to hydroxyl and carbonyl reaction to achieve fluorine substitution, is widely used in the synthesis of fluorine-containing organic natural products, such as preparation