论文部分内容阅读
Milrinone 是氨联吡啶酮的一种衍生物,应用后其血流动力学改善究系由血管扩张,抑或正性肌力与血管扩张的综合作用所致尚有争议。最近根据收缩终末期的生理现象建立了左室收缩状态的一些非负荷依赖性敏感指标。本文采用这些指标来测定对照期和输入 milrinone 时左室的收缩性,以探讨此药对心脏收缩的影响。方法:受试者为11名血压正常的男性,18～31岁,无心肺病史,心脏检查正常。试前予阿托品
Milrinone is a derivative of aminopyridone. It is controversial after its application to improve hemodynamics in the study by the combined effects of vasodilation, or inotropic and vasodilation. Recently based on the phenomenon of end-stage contraction of the left ventricular systolic established some non-load-dependent sensitivity index. In this paper, we use these parameters to determine the control period and left ventricular contractility when milrinone is administered to investigate the effect of this drug on cardiac contractility. Methods: The subjects were 11 men with normal blood pressure, 18-31 years old, without a history of heart and lung disease, and their heart tests were normal. Pre-test atropine