粟粒性结核由于常被基础疾病所掩盖,且早期细菌学证实不易,故诊断有时相当困难。本文对骨髓针吸活检对粟粒性结核的诊断价值进行了评价。方法选择1988～1992年拟诊粟粒性结核的8例住院患者为研究对象,以同期5例患肺结核而临床及X线无粟粒性结核证据的患者为对照组。住院后立即以普通骨髓穿刺针和注射器在患者胸骨处抽取骨髓,首先涂片一张抗酸染色直接镜检抗酸杆菌,此后将1ml骨髓液滴在滤纸上使其凝固。10～15分钟后用福尔马林固定。标本经脱水、石蜡包埋后,连续切片30 Miliary tuberculosis is often difficult to diagnose because it is often masked by underlying diseases and early bacteriological confirmation is not easy. In this paper, the diagnostic value of bone marrow aspiration biopsy for miliary tuberculosis was evaluated. Methods Eight inpatients with suspected miliary tuberculosis from 1988 to 1992 were selected as study subjects. Five patients with tuberculosis and no evidence of miliary tuberculosis on X-ray were selected as the control group. Immediately after hospitalization, the bone marrow was aspirated from the sternum of a patient by using a common bone marrow aspirating needle and a syringe. First, an acid-fast stain for acid-fast bacillus was smear-coated, and 1 ml of bone marrow was allowed to solidify on the filter paper. After 10 to 15 minutes with formalin fixation. Specimens were dehydrated and embedded in paraffin for 30 consecutive sections