本文综述了高效液相色谱中描述溶质分子结构参数与色谱保留行为关系的五大类数学模型，并对各种模型的优、缺点进行了评述。 In this paper, five kinds of mathematical models for describing the relationship between solute molecular structure parameters and chromatographic retention behavior in high performance liquid chromatography (HPLC) are reviewed. The advantages and disadvantages of various models are also reviewed.