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在糖尿病视网膜病变的进展阶段,新生血管形成的机制尚不明确。最近的研究发现,瘦素在体外具有血管生成的作用,且在体内诱导新生血管形成。本研究的目的是探讨血浆瘦素水平与糖尿病视网膜病变严重程度的关系。对象与方法 受试者为70例仅接受磺脲类药物治疗的2型糖尿病患者,另有
The mechanism of neovascularization is not clear in the progression of diabetic retinopathy. Recent studies have found that leptin has an angiogenic effect in vitro and induces neovascularization in vivo. The purpose of this study was to investigate the relationship between plasma leptin levels and the severity of diabetic retinopathy. Subjects and Methods The subjects were 70 patients with type 2 diabetes who received sulfonylureas alone and another