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目的探讨星夏涤痰饮方联合化疗治疗晚期痰瘀阻肺型非小细胞肺癌的临床效果。方法对136例痰瘀阻肺型晚期非小细胞肺癌患者随机分为两组,中西医结合组(69例)采用星夏涤痰饮加减联合化疗治疗,单纯西医治疗组(67例)采用化疗,对两组治疗前后的KPS评分对比,肿瘤瘤体大小前后对比。对两组KPS评分及瘤体大小进行统计学处理。结果1两组病例提高患者生活质量分别为31.34%(单纯西医组)与59.42%(中西医结合组),经统计学处理,有显著差异(P<0.05);2两组病例CR+PR+SD分别为57.35%(单纯西医组)与60.29%(中西医结合组),经统计学处理,无差异(P>0.05)。结论星夏涤痰饮联合化疗较单纯化疗能够显著提高痰瘀阻肺型肺癌患者生活质量。
Objective To investigate the clinical effect of Xingxia Ditan Recipe combined with chemotherapy in the treatment of advanced non-small cell lung cancer with phlegm-stasis syndrome. Methods One hundred and sixty-six patients with advanced non-small cell lung cancer with phlegm-stasis syndrome were randomly divided into two groups. The combination of traditional Chinese and western medicine (69 cases) was treated with Xingxia Ditan Tan Decoction combined with chemotherapy, while the Western medicine group (67 cases) Chemotherapy, KPS scores before and after treatment compared to the size of the tumor before and after contrast. KPS scores and tumor size of two groups were statistically analyzed. Results 1 The quality of life of patients in two groups were significantly improved (31.34% (pure WM group) and 59.42% (integrated TCM-WM group), respectively, with statistical significance (P <0.05) SD were 57.35% (pure Western group) and 60.29% (integrated traditional Chinese and Western medicine group), no statistical difference (P> 0.05). Conclusion Xing Xia Di Phlegm Decoction combined with chemotherapy alone can significantly improve the quality of life of patients with lung phlegm and stasis lung cancer.