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目的 了解海南州藏系绵羊鼠疫流行情况,为鼠疫的预防预警提供理论依据.方法 采集藏系绵羊(以下简称为藏羊)血清,应用鼠疫间接血凝(Indirect hemagglutination test,IHA)和鼠疫胶体金(gold immunochromatography assay,GICA)两种方法分别检测藏羊血清鼠疫FI抗体.结果 对2016年采集自海南州的1 734份藏羊血清进行检测,共检出阳性血清28份,两种方法的相符率为100.00％,其中鼠疫F1抗体滴度1:20的16份、1:40的9份、1:80的3份.结论 海南州存在藏羊鼠疫流行,特别是在海南州兴海县,应加强藏羊鼠疫的监测.“,”Objective To understand the epidemic situation of plague of Tibetan sheep in Hainan Prefecture,in order to provide theoretical basis for future plague prevention and early warning.Methods The serum of Tibetan sheep was collected.We applied IHA and GICA,these two methods to test the serum of Tibetan sheep in Hainan Prefecture.Results A total of 1 734 Tibetan sheep serum was tested with the methods of IHA and GICA respectively,a total of 28 positive serum were detected,and the match rate of the two methods was 100.00％,among which,the F1 of the plague 1:20 antibody titer was 16,1:40 was 9,1:80 was 3.Conclusion There are Tibetan sheep plague epidemic in the region.Especially in Xinghai County of Hainan Prefecture,should strengthen the monitoring work of Tibetan sheep plague.