论文部分内容阅读
[目的]观察中医药序贯疗法联合柳氮磺吡啶治疗溃疡性结肠炎疗效。[方法]使用随机平行对照方法,将80例住院患者按抛硬币法随机分为两组。对照组40例柳氮磺吡啶,1g/次,4次/d。治疗组40例中医序贯疗法,白头翁、地榆、黄芩各10g,黄连6g,1剂/d,水煎300mL,3次/d,口服;地榆、黄柏各30g,石菖蒲20g,苦参10g,水煎100mL,睡前保留灌肠;症状缓解后,炙黄芪、炒白芍各20g,白芷、炒白术各10g,白及6g,水煎300mL,3次/d,灌肠同时保留前期灌肠;柳氮磺吡啶治疗同对照组。连续治疗25周为1疗程观测临床症状、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈25例,显效10例,有效2例,无效3例,总有效率92.50%。对照组痊愈11例,显效8例,有效6例,无效15例,总有效率62.50%。治疗组疗效优于对照组(P<0.05)。不良反应治疗组低于对照组(P<0.05)。复发情况治疗组低于对照组(P<0.05)。[结论]中医药序贯疗法联合柳氮磺吡啶治疗溃疡性结肠炎效果显著,值得推广。
[Objective] To observe the curative effect of sequential therapy of traditional Chinese medicine and sulfasalazine on ulcerative colitis. [Methods] Using randomized parallel control method, 80 inpatients were randomly divided into two groups according to the coin tossing method. Control group, 40 cases of sulfasalazine, 1g / time, 4 times / d. Treatment group 40 cases of sequential treatment of Chinese medicine, Pulsatilla, Burnet, Scutellaria the 10g, Coptis 6g, 1 / d, decoction 300mL, 3 times / d, orally; Burnet, Cork 30g, Shichangpu 20g, Sophora 10g, decoction 100mL, retention enema before going to sleep; symptoms relieved, Sunburn Astragalus, fried white peony root of the 20g, Angelica, Atractylodes 10g, white and 6g, decoction 300mL, 3 times / d, Sulfasalazine treatment with the control group. Continuous treatment of 25 weeks for a course of treatment of clinical symptoms, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Results] The treatment group cured 25 cases, markedly effective in 10 cases, effective in 2 cases, ineffective in 3 cases, the total effective rate was 92.50%. The control group recovered in 11 cases, markedly effective in 8 cases, effective in 6 cases, ineffective in 15 cases, the total effective rate was 62.50%. The treatment group was better than the control group (P <0.05). Adverse reactions in the treatment group were lower than those in the control group (P <0.05). The recurrence was lower in the treatment group than in the control group (P <0.05). [Conclusion] The sequential treatment of traditional Chinese medicine combined with sulfasalazine has a significant effect in the treatment of ulcerative colitis and is worth promoting.