基因疫苗(gene vaccine)又称DNA疫苗(DNA vaccine)或核酸疫苗(nucleic acid vaccine),即将编码特异性抗原多肽或蛋白的基因克隆到真核表达载体上,然后经一定途径进入机体内,使外源基因在活体内表达、产生的抗原激活机体的免疫系统,从而诱导特异性的体液免疫和细胞免疫应答,以达到预防和治疗疾病的目的。基因疫苗由抗原编码基因及质粒载体两部分组成。抗原基因可以是单个基因或完 Gene vaccine (DNA vaccine) or nucleic acid vaccine (nucleic acid vaccine), about to encode a specific antigen peptide or protein gene cloned into the eukaryotic expression vector, and then by some way into the body, so that Exogenous genes expressed in vivo, the resulting antigen activation of the body’s immune system, thereby inducing specific humoral and cellular immune response, so as to achieve the purpose of prevention and treatment of diseases. Gene vaccine consists of antigen encoding gene and plasmid vector. The antigen gene can be a single gene or end