肿瘤血管生成是所有实体肿瘤的共同特征,是实体肿瘤生长和转移必须依赖的病理学基础,与肿瘤的生长、侵袭转移关系极为密切。现已证实,不同实体肿瘤血管内皮细胞所表达的生长因子及其受体均有共性,因此抗血管生成靶向治疗已经成为肿瘤治疗的重要策略。目前,已有数 Tumor angiogenesis is a common feature of all solid tumors, which is the pathological basis that solid tumor growth and metastasis must rely on. It has a close relationship with tumor growth, invasion and metastasis. It has been confirmed that different solid tumor vascular endothelial cells expressed by growth factors and their receptors are common, so anti-angiogenesis targeted therapy has become an important strategy for cancer treatment. At present, there are already a few