Proton magnetic resonance spectroscopy(1H MRS)can provide specific biochemical information within breast lesions and the elevated composite choline concentration as a useful diagnostic tool has been used to distinguish malignant from benign breast lesions,early evaluate response to therapy and predict prognosis.However,several obstacles including poor spatial resolution,low signal-to-noise ratio(SNR),long acquisition time and the difficulty of"extra"lipid suppression may have a negative impact on the routine application of in vivo 1H MRS for human breast cancer.At present,optimization H MRS methodology for breast studies has been performed.