甲醇通过铑的作用羰基化合成乙酸的反应,被认为是在有机化学领域的重大成就。在为数众多的催化剂中,铑的小分子配合物以其反应条件温和、高活性和高选择性而被广泛研究。其中Monsanto的均相催化法成功地应用于大规模的工业生产。然而,均相催化剂存在着一些不可避免的缺点,例如,不稳定、对设备的特别要求及铑的回收工艺复杂等。近年来,科学家们 The reaction of methanol with acetic acid via carbonylation of rhodium is considered to be a significant achievement in the field of organic chemistry. Among a large number of catalysts, rhodium small-molecule complexes are widely studied for their mild reaction conditions, high activity and high selectivity. Among them, Monsanto’s homogeneous catalysis has been successfully applied to large-scale industrial production. However, there are some unavoidable disadvantages of homogeneous catalyst, such as instability, special requirements for equipment and complicated process of rhodium recovery. In recent years, scientists