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目的:观察磷酸肌酸(creatine phosphate,CP)和参麦注射液治疗小儿急性病毒性心肌炎的临床疗效。方法:将病毒性心肌炎住院患儿108例随机分为治疗组和对照组各54例,治疗组应用CP加常规药物、对照组则用参麦注射液加常规药物规范治疗。观察治疗前后两组患者的症状体征、心电图、心脏彩超、心肌酶谱的变化情况。结果:CP疗效显著,两组间差异有统计学意义(P<0.01)。结论:CP能更快更好地缓解症状、减少心律失常的发作、降低心肌酶、迅速恢复扩大的心脏以及明显的缩短病程。
Objective: To observe the clinical efficacy of creatine phosphate (CP) and Shenmai injection in the treatment of acute viral myocarditis in children. Methods: A total of 108 hospitalized children with viral myocarditis were randomly divided into treatment group (54 cases) and control group (54 cases). The treatment group was given CP plus conventional drugs while the control group was treated with Shenmai injection plus conventional drugs. Before and after treatment, the symptoms and signs, electrocardiogram, echocardiography and myocardial enzymes in both groups were observed. Results: The effect of CP was significant, with significant difference between the two groups (P <0.01). Conclusion: CP can relieve symptoms faster and better, reduce the incidence of arrhythmia, reduce myocardial enzymes, quickly restore the enlarged heart and significantly shorten the course of the disease.