论文部分内容阅读
作者报告从1969年1月至1980年12月间连续观察的28例狼疮性肾炎患者.28例均符合美国风湿病协会的SLE临床诊断标准.其中25例肾活检或尸检证实为狼疮性肾炎组织学改变.应用血液透析法的指征与非狼疮性肾功衰竭者相似:内生肌酐廓清率持续减少至10ml/分以下,同时伴有尿毒症的症状与体征.在早期作者用-kiil平板透析器,每周治疗18～30小时.继而采用中空纤维透析器,每周治疗9～15小时.血液透析要使血尿素氮及肌酐浓度分别维持在透析前的100mg/100ml和20mg/100ml以下,才算达到目的.28例开始均采用了长期血液透析法治疗,多数患者继而行肾移植术和不卧床的持续腹膜透析.
The authors reported 28 consecutive cases of lupus nephritis observed from January 1969 to December 1980. All of the 28 patients met the criteria of the SLE clinical diagnostic criteria of the American College of Rheumatology, 25 of whom were confirmed by renal biopsy or autopsy as lupus nephritis Changes in the application of hemodialysis indications and non-lupus renal failure were similar: endogenous creatinine clearance rate continued to decrease to 10ml / min or less, accompanied by symptoms and signs of uremia in early authors with -kiil plate Dialyzer, weekly treatment of 18 to 30 hours, followed by a hollow fiber dialyzer, weekly treatment of 9 to 15 hours hemodialysis so that blood urea nitrogen and creatinine concentrations were maintained at 100mg / 100ml and 20mg / 100ml before dialysis , Only to achieve the purpose of .28 cases were started using long-term hemodialysis treatment, followed by renal transplantation in most patients and ambulatory continuous peritoneal dialysis.