宫颈微偏腺癌(minimal deviation adenocarcinoma,MDA)具有高侵袭性,预后差,早期由于缺乏明显的临床及病理学特征,细胞形态及组织结构又酷似正常宫颈内膜腺体,故临床及病理诊断的漏、误诊率非常高,需要经多次宫颈活检或锥切术后方可确诊。本文收集4例MDA,对其临床症状、病理形态、免疫组化特征进行分析。 Minimal deviation of adenocarcinoma (MDA) has high invasiveness and poor prognosis. Early due to the lack of obvious clinical and pathological features, cell morphology and tissue resemble normal endocervical glands, so the clinical and pathological diagnosis Of the drain, the misdiagnosis rate is very high, need to be confirmed by multiple cervical biopsy or conization. This article collected 4 cases of MDA, its clinical symptoms, pathological features, immunohistochemical characteristics were analyzed.