液-液提取结合薄层层析法可鉴别许多药物,包括市售剂型和生物体中的药物。该系统利用有选择性的pH 提取与内标相结合,灵敏度范围可达微克水平以下。本法具有操作迅速、设备简单和容易掌握的优点,可应用于包括临床和法律实施所需的毒物学。医疗部门经常遇到必需对急诊病人体内药物进行鉴别。出现的问题可能有误服过量药品或滥用非法药品以致产生过量反应或特异体质反应。此时采用的分析系统应能以≤1μg/1份样品的灵敏度对体液中(常为血或尿)的化合物进行定性和定量。法律机构常遇到疑含有某种药物或药物残 Liquid-liquid extraction combined with thin-layer chromatography can identify many drugs, including those in commercial dosage forms and organisms. The system utilizes selective pH extraction combined with an internal standard, with sensitivity in the microgram range. This method has the advantages of rapid operation, simple equipment and easy to grasp, which can be applied to toxicology including clinical and legal implementation. Medical departments often encounter the need to identify patients in emergency medicine. Problems that arise may have been caused by overuse of drugs or abuse of illicit drugs resulting in over-response or idiosyncratic reactions. The analytical system used at this time should be capable of quantifying and quantifying compounds in body fluids (usually blood or urine) at a sensitivity of ≤1 μg / sample. Legal agencies often encounter suspected of containing some kind of drug or drug residues