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目的:评价不同剂量丙种球蛋白与阿司匹林联用治疗川崎病患者的临床疗效和护理方法。方法:选取妇女儿童医院2013年6月—2014年12月间收治的川崎病患者76例,将其分为对照组患者和观察组患者各38例;对照组患者均给予丙种球蛋白与阿司匹林治疗和常规护理,观察组患者均给予丙种球蛋白与阿司匹林治疗和综合护理干预,比较两组患者的临床疗效和护理方法。结果:观察组患者治疗后平均退热时间为(2.2±0.7)d显著短于对照组为(4.7±1.3)d(P<0.05);颈部淋巴结肿大消失时间为(3.6±1.5)d显著短于对照组为(6.9±2.1)d(P<0.05);观察组患者治疗的依从性和护理满意度分别为(89.47%)和(92.10%)均显著高于对照组患者(57.89%和73.7%)(P<0.05)。结论:高剂量丙种球蛋白与阿司匹林联用治疗川崎病患者,并辅以综合护理干预,能有效改善患儿临床症状,有效提高了家属对治疗的依从性和护理满意度。
Objective: To evaluate the clinical efficacy and nursing of Kawasaki disease in patients with Kawasaki disease treated with different doses of gamma globulin and aspirin. Methods: A total of 76 patients with Kawasaki disease who were admitted to Women’s and Children’s Hospital from June 2013 to December 2014 were selected and divided into control group and observation group, with 38 cases in each group. Patients in control group were treated with gamma globulin and aspirin And routine nursing. Patients in the observation group were treated with gamma globulin and aspirin and comprehensive nursing intervention. The clinical efficacy and nursing methods were compared between the two groups. Results: The mean duration of antipyretic fever in observation group was (2.2 ± 0.7) days after treatment was significantly shorter than that in control group (4.7 ± 1.3 days) (P <0.05). The disappearance time of cervical lymph node enlargement was (3.6 ± 1.5) days (6.9 ± 2.1) d (P <0.05). The treatment compliance and nursing satisfaction in the observation group were significantly higher than that in the control group (89.47%) and (92.10%) (57.89% And 73.7%) (P <0.05). Conclusion: High dose gamma globulin combined with aspirin in patients with Kawasaki disease, combined with comprehensive nursing intervention can effectively improve the clinical symptoms of children, effectively improving the compliance of family members and nursing satisfaction.