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目的探讨海尔福口服液对地方性砷中毒患者的治疗效果。方法选择已明确诊断的地方性砷中毒患者35例,按规定剂量服药,分2个疗程,每疗程服药30 d,2疗程间隔2周,每疗程结束取尿测定尿砷(As)和尿羟脯氨酸(Hop)含量,并观察病情变化。结果尿As第1疗程虽有一定程度降低,但不明显,第2疗程尿As明显低于治疗前(P<0.05);尿Hop治疗前后比较,两疗程结果均降低,第2疗程比治疗前明显降低(P<0.05);患者自觉症状明显改善。结论海尔福口服液可改善地方性砷中毒患者的自觉症状,对患者尿As和尿Hop有一定影响。
Objective To investigate the therapeutic effect of Haier Fu oral liquid on patients with endemic arsenism. Methods Thirty-five patients with endemic arsenism who had been confirmed diagnosed were randomly divided into two groups according to the prescribed dose. The course of treatment was 30 days. The course of treatment was 2 weeks. At the end of each course, urinary arsenic (As) and urinary excretion Proline (Hop) content, and observe the changes in condition. Results Although the first course of urinary As decreased to a certain extent, the urinary As in the second course of treatment was significantly lower than before treatment (P <0.05); before and after urinary Hop treatment, the results of the two courses of treatment were both lower than the first course of treatment Significantly lower (P <0.05); patients with symptoms improved significantly. Conclusion Haier Fu oral liquid can improve the symptoms of endemic arsenism in patients with As and urinary Hop have some impact.