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本文观察了镉（ＣｄＣｌ_２）、砷（Ａｓ_２Ｏ_３）及其联合作用对大鼠免疫功能的影响。结果表明：持续６周染毒时，见高剂量镉组（４．６８ｍｇ／ｋｇ）对外周血淋巴细胞α－醋酸萘酯酶（ＡＮＡＥ）活性；低剂量砷组（１．３８ｍｇ／ｋｇ）和高剂量砷组（６．９０ｍｇ／ｋｇ）对血清溶菌酶均呈抑制作用。两者联合作用（Ｃｄ低＋Ａｓ低，Ｃｄ高＋Ａｓ高）时，见镉有拮抗砷抑制血清溶菌酶的作用。在三周交替染毒中，发现在单独作用时，高剂量砷组对血清ＩｇＧ和血清溶菌酶的作用均表现为抑制，而低剂量的镉（０．９３７ｍｇ／ｋｇ）则对血清溶菌酶具有兴奋作用。联合作用方面，见在对血清ＩｇＧ和溶菌酶的影响上，镉亦表现出拮抗砷的免疫抑制作用，且先染镉组比后染镉组的作用稍强。
The effects of cadmium (CdCl 2), arsenic (As_2O_3) and their combined effects on immune function in rats were observed. The results showed that ANAE activities of peripheral blood lymphocytes in high dose cadmium group (4.68 mg / kg) and low dose arsenic group (1.38 mg / kg) and High-dose arsenic group (6.90mg / kg) showed inhibition on serum lysozyme. The combination of the two (Cd low + As low, Cd high + As high), see cadmium antagonism of arsenic inhibition of serum lysozyme role. In the three weeks of alternate exposure, we found that the effects of high dose arsenic group on serum IgG and serum lysozyme were both inhibited when treated alone, whereas low dose cadmium (0.937 mg / kg) had a significant effect on serum lysozyme Excitement. In the combined action, cadmium also showed antagonistic arsenic immunosuppressive effects on serum IgG and lysozyme, and the effect of cadmium-exposed group was slightly stronger than that of cadmium-exposed group.