论文部分内容阅读
目的分析高血压患者超重与心血管疾病危险性的关系。方法将2002年1月至2005年6月大连市老年病医院心内科符合1999年 WHO/ISH 高血压诊断标准的183例原发性高血压患者按体重指数(BMI)分为2组:超重高血压组(BMI≥25)和非超重高血压组(BMI<25),比较2组主要心血管疾病危险因素水平及临床特征。结果超重高血压组较非超重高血压组总胆固醇(TC)、甘油三酯(TG)、血糖(GLU)、C反应蛋白(CRP)增高,而高密度脂蛋白胆固醇(HDL-C)降低;收缩压(SBP)及舒张压(DBP)均随着BMI 的增加而明显增高;颈动脉斑块、冠心痛、糖尿病、高血脂的发生率增加(P 均<0.05)。结论超重高血压患者心血管疾病危险因素明显增加,应积极控制体重至正常水平,对预防心血管疾病的发生及发展有重要意义。
Objective To analyze the relationship between the risk of overweight and cardiovascular disease in hypertensive patients. Methods From January 2002 to June 2005, 183 patients with essential hypertension who met the WHO / ISH Hypertension Diagnostic Criteria in 1999 at the Department of Cardiology, Geriatric Hospital of Dalian City were divided into two groups according to body mass index (BMI): overweight Blood pressure group (BMI≥25) and non-overweight hypertension group (BMI <25). The risk factors and clinical features of the two major cardiovascular diseases were compared. Results The levels of total cholesterol (TC), triglyceride (TG), blood glucose (GLU) and C-reactive protein (CRP) and HDL-C in hypertensive group were significantly higher than those in non-overweight group Systolic blood pressure (SBP) and diastolic blood pressure (DBP) increased with the increase of BMI. The incidence of carotid artery plaque, coronary heart disease, diabetes and hyperlipidemia increased (all P <0.05). Conclusion The risk factors of cardiovascular disease in overweight hypertensive patients increased significantly, and should be actively controlled body weight to normal levels, the prevention of cardiovascular disease occurrence and development of great significance.