人乳腺珠蛋白 (hMAM)为乳腺组织特异性蛋白 ,是一种新的可能具有临床应用前景的乳腺癌标志物。近几年国内外研究者对hMAM在乳腺、淋巴结、外周血和骨髓中的表达及其与乳腺癌的关系做了大量工作 ,结果不尽相同 ,提出了不同的观点。现对hMAM及其基因在乳腺癌检测中的研究现状作一综述 Human mammary gland globin (hMAM) is a breast tissue-specific protein and is a new marker of breast cancer that may have clinical application prospects. In recent years, researchers at home and abroad have made a great deal of work on the expression of hMAM in breast, lymph node, peripheral blood and bone marrow and its relationship with breast cancer. The results are not the same, and different views are put forward. The current research status of hMAM and its gene in breast cancer detection are reviewed