The relationship between δ18O in precipitation and climatic factors is analyzed based on　the observation of δ18O in precipitation and meteorological data in the four years from 1992 to 1995 at Tuotuohe Meteorological Station, Tibetan Plateau. Almost all the precipitation on the Tibetan Plateau is concentrated on the warm period of the year, while in the dry cold period, there is only a few precipitation events. Because the factors affecting δ18O in precipitation is rather complicated and the air temperature does not change too much in the precipitation season, the distribution of δ18O in precipitation with air temperature is therefore scattered. In this paper, the relationship between the averages of each meteorological factor and the corresponding δ18O in precipitation is analyzed. The analysis results indicate that there is an obvious positive correlation between the monthly δ18O and temperature in the 4 years: whenever the air temperature increases 1℃, δ18O in precipitation will increase 0. 5‰. No correlation can be observed between relative humidity and B18O in precipitation. There still can not find any correlation between the annual air temperature and annual δ18O in precipitation in the 4 years probably due to the very short time series of the observation and the little annual air temperature variations. The relationship between δ18O in precipitation and climatic factors is based on the observation of δ18O in precipitation and meteorological data in the four years from 1992 to 1995 at Tuotuohe Meteorological Station, Tibetan Plateau. Almost all the precipitation on the Tibetan Plateau is concentrated on the because of factors affecting δ18O in precipitation is rather complicated and the air temperature does not change too much in the precipitation season, the distribution of δ18O in precipitation with air temperature is caused scattered. In this paper, the relationship between the averages of each meteorological factor and the corresponding δ18O in precipitation is analyzed. The analysis results indicate that there is an obvious positive correlation between the monthly δ18O and temperature in the 4 years: whenever the air temperature increases by 1 ℃, δ18O in precipit There will be no correlation between the annual air temperature and annual δ18O in precipitation in the 4 years probably due to the very short time series of the observation and the little annual air temperature variations.