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用人胚肺成纤维细胞的体外转化实验检测出甲基丙烯酸环氧丙酯可诱导人胚肺成纤维细胞形态学改变，转化细胞核浆比例增大，排列紊乱，交叉重叠生长。从转化集落分离的细胞可被较低浓度的刀豆凝集素Ａ凝集，在半固体琼脂内非贴壁依赖生长。转化细胞的染色体发生结构和数目改变。上述结果表明：甲基丙烯酸环氧丙酯具有诱导人胚肺成纤维细胞恶性转化的作用，预示它可能对人具有潜在的致癌危险性。
In vitro transformation assay of human embryo lung fibroblasts detected that glycidyl methacrylate could induce the morphological changes of human embryo lung fibroblasts, increase the proportion of transformed cyto-plasmas, disordered arrangement and cross-over growth. Cells isolated from the transformed colonies could be agglutinated with the lower concentration of bean agglutinin A and grow non-anchored in the semi-solid agar. The chromosomal structure and number of transformed cells change. The above results show that glycidyl methacrylate can induce the malignant transformation of human embryonic lung fibroblasts, indicating that it may have a potential carcinogenic risk to humans.