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本文报告12例成人慢性原发性血小板减少性紫癜(简称ITP),应用免疫抑制治疗17个疗程的结果,并与文献报告的94例作了比较。全部病例对脾切除及皮质激素均不起反应。多数病例单用一种免疫抑制剂和接受一个疗程的治疗,同时每天口服强的松20～40毫克,约有33％的病例有良好反应。疗效评级分为:“显效”(指血液学与临床完全缓解,停药后较长时间无复发);“良好”(虽取得完全缓解,但仍需免疫抑制剂维持);“较差”及“失败”。后两级均属无效。治疗结果见表。
This article reports 12 cases of adult chronic thrombocytopenic purpura (referred to as ITP), the application of immunosuppressive therapy for 17 courses of treatment results, and 94 cases reported in the literature were compared. All cases of splenectomy and corticosteroids are not responsive. In most cases, an immunosuppressant and a single course of treatment were administered alone. 20 to 40 mg of prednisone was administered orally daily, and about 33% of the patients had a good response. The efficacy ratings were divided into: “markedly effective” (referring to hematology and clinical complete remission, no recurrence after a long period of withdrawal); “good” (although complete remission was needed but still maintained with immunosuppressants); “poor” and “failure”. After the two are invalid. Treatment results shown in the table.