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自本世纪初Von pirquet提出免疫复合物的致病性以来,人们对免疫复合物的生理及病理意义的认识逐渐加深。目前,大致上可将用于检测及研究体液中循环免疫复合物的方法和技术归纳为直接从体液中检测循环免疫复合物的抗原非特异性方法、抗原特异性方法以及循环免疫复合物组份分析技术。本文仅就此近年进展做一简要报道。 1 抗原非特异性方法 用于检测循环免疫复合物的方法常常建立在对抗原抗体复合物特殊的物理化学性质及生物学性质的认
Since Von Pirquet proposed the pathogenicity of immune complexes at the beginning of this century, people’s understanding of the physiological and pathological significance of immune complexes has gradually deepened. Currently, methods and techniques for detecting and studying circulating immune complexes in bodily fluids can generally be summarized as non-specific methods of antigen detection of circulating immune complexes directly from bodily fluids, antigen-specific methods, and analysis of components of circulating immune complexes technology. This article only makes a brief report on this recent progress. Non-specific antigenic methods Methods for the detection of circulating immune complexes are often based on the identification of the specific physico-chemical and biological properties of the antigen-antibody complex