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1990~1991年在1∶1配比病例对照研究中,应用危险状态分析法(ASRS)对广东地区79例女性原发性肺癌进行分析。结果显示:慢性支气管炎、丈夫吸烟指数≥141、使用避孕药,三者共同构成广东地区女性肺癌高危险状态,其调整OR值分别为10.91、4.53、6.55,调整人群归因危险度为11.50%、64.15%、8.24%,综合人群归因危险度为75.41%。秩相关分析提示:作为肺癌基本病因之一的慢性支气管炎,在吸烟,被动吸烟以及厨房烟熏、不良通风存在的情况下,增强了女性肺癌的危险性。
From 1990 to 1991, in a 1:1 matched case-control study, 79 cases of female primary lung cancer in Guangdong Province were analyzed using ASRS. The results showed that chronic bronchitis, husband’s smoking index ≥ 141, use of contraceptives, the three together constitute a high risk of lung cancer in women in Guangdong Province, the adjusted OR value was 10.91, 4.53, 6.55, adjust the crowd Because the risk is 11.50%, 64.15%, 8.24%, the overall population attributable risk is 75.41%. Rank correlation analysis suggests that chronic bronchitis, one of the basic causes of lung cancer, increases the risk of female lung cancer in the presence of smoking, passive smoking, and kitchen smoke and poor ventilation.