八十年代,钙生物学功能和钙调蛋白的研究形成了高潮。最近有人报道一种特异存在于肿瘤组织中的钙调蛋白——癌调蛋白,引起医学界人士的关注。一、钙调蛋白(Calmodulin)钙调蛋白是一种广泛存在,能与钙离子结合并有细胞调节功能的蛋白质。其肽链含148个氨基酸残基,具有四个钙结合区,不含半胱氨酸和羟脯氨酸,无种族特异性。人、牛和鸡钙调蛋白的氨基酸顺序完全相同,与电鳗的钙 In the 1980s, the study of calcium biological function and calmodulin formed a climax. Recently, it has been reported that a calmodulin, a calmodulin that specifically exists in tumor tissues, has attracted the attention of the medical community. 1. Calmodulin Calmodulin is a ubiquitous protein that binds to calcium and has cellular regulatory functions. Its peptide chain contains 148 amino acid residues, has four calcium binding regions, contains no cysteine ​​and hydroxyproline, and is not race specific. The amino acid sequence of human, bovine and chicken calmodulin is exactly the same,