目的　探讨口腔粘膜嗜酸性溃疡的病因、临床病理表现、诊疗与预后, 以期对该病有所了解和认识。方法　对8 例口腔粘膜嗜酸性溃疡病人进行临床病理分析。结果　口腔粘膜嗜酸性溃疡界限清楚, 表面清洁,所有病例均位于舌部且为单发,3 例有复发史, 镜下以固有层嗜酸性细胞为特点。结论　口腔粘膜嗜酸性溃疡是一种少见的自限性良性疾病, 好发于老人和儿童, 病因不清, 可能与创伤有关, 诊断根据临床病理表现, 治疗采用活检切除和完全切除法, 预后较好 Objective To investigate the etiology, clinicopathological features, diagnosis and prognosis of oral mucosal eosinophilic ulcer in order to understand and recognize the disease. Methods Eight cases of oral mucosal eosinophilic ulcer patients were analyzed clinically and pathologically. Results Oral mucosal eosinophilic mucosal demarcation was clear, the surface was clean, all cases were located in the tongue and solitary, and 3 patients had a history of recurrence. The eosinophils were characterized by eosinophils. Conclusion Oral mucosal eosinophilic ulcer is a rare self-limiting benign disease, which occurs predominantly in the elderly and children. The etiology is unclear. It may be related to trauma. The diagnosis is based on the clinicopathological findings. The treatment is biopsy and complete resection. The prognosis is it is good