棉酚是一种二聚倍半萜,存在于棉花的种子和皮中,50年代后期证实对人有抗生育作用,能抑制精子发生和精子活力,作为一种强效男用避孕药。然而在实际应用中发现有一些副作用,如低血钾、嗜睡和性欲减退,长期应用也可能产生对睾丸功能的不可逆性影响。许多学者提出经纯化的棉酚右旋异构体对田鼠抑制精子发生无效,而认为棉酚左旋 Gossypol is a dimeric sesquiterpene found in the seeds and barks of cotton. It was demonstrated in the late 1950s to have an anti-fertility effect on humans that inhibits spermatogenesis and sperm motility as a potent male contraceptive. However, in practice, some side effects such as hypokalemia, lethargy and loss of libido have been found. Long-term application may also have an irreversible effect on testicular function. Many scholars have suggested purified dextrose isomers of gossypol on voles inhibit vomiting is invalid, and that gossypol levo