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神经干细胞是近年来神经科学领域研究的一个热点。神经干细胞可来源于胚胎干细胞和成年干细胞,前者包括早期胚胎细胞和胎儿神经组织细胞,由于从胚胎获取干细胞面临伦理学的束缚,从成年来源的神经干细胞将是未来临床应用更具可行性的途径。成年来源的神经干细胞包括存在于成年神经组织中的干细胞和从其他组织中分化得到的干细胞,其中骨髓基质细胞具有多分化潜能,在适当的条件下可以诱导分化出神经于细胞,目前备受关注。
Neural stem cells are a hot spot in the field of neuroscience in recent years. Neural stem cells can be derived from embryonic stem cells and adult stem cells, the former including early embryonic cells and fetal neural tissue cells. Due to the ethical bondage of stem cells obtained from embryos, neural stem cells from adult sources will be more feasible for future clinical application . Adult-derived neural stem cells include stem cells present in adult nerve tissue and stem cells differentiated from other tissues, wherein bone marrow stromal cells have pluripotency potential and can induce differentiation of neural cells into cells under appropriate conditions, and are currently receiving much attention .