流行病学显示我国90%以上的慢性肝衰竭与乙肝病毒(HBV)感染有关。我国现有慢性乙型肝炎(choronic hepatitis B,CHB)患者约2000万例,每年0.1%~0.3%的患者发展为慢性肝衰竭,病死率达50%~60%[1]。为了解HBV DNA病毒载量对慢性肝衰竭的影响,我们对2006-2008年5家医院收治的 Epidemiology shows that more than 90% of chronic liver failure in our country is related to hepatitis B virus (HBV) infection. There are about 20 million CHB patients in our country, with 0.1% -0.3% of patients developing chronic liver failure each year, with a mortality rate of 50% -60% [1]. To understand the impact of HBV DNA viral load on chronic liver failure, we evaluated the efficacy of HBV DNA in five hospitals treated in 2006-2008