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目的探讨穿心莲内酯总磺化物(喜炎平注射液),治疗手足口病临床疗效。方法对65例手足口病分治疗组35例和对照组30例,治疗组静点喜炎平0.2ml·kg-1·次-1+0.9%NS50~100ml稀释静滴,Qd,3d,利巴韦林7.5mg·kg-1·次-1+5%GS50~100ml稀释静滴,Qd,3d。结果床疗效满意,治疗组在退热、退疹方面均优于对照组(P<0.05)。结论喜炎平治疗手足口病临床疗效好,安全性高,疗程短,无不良反应。
Objective To investigate the clinical efficacy of andrographolide total sulfonate (Xiyanping injection) in the treatment of hand-foot-mouth disease. Methods 65 cases of hand-foot-mouth disease were divided into treatment group (35 cases) and control group (30 cases). The treatment group was treated with Xiyanping 0.2ml · kg-1 · -1 + 0.9% NS50 ~ 100ml diluted intravenous drip, Qd, 3d, Ribavirin 7.5mg · kg -1 · -1 + 5% GS50 ~ 100ml diluted intravenous infusion, Qd, 3d. Results The curative effect of the bed was satisfactory, and the treatment group was better than the control group in the aspects of fever and rutting (P <0.05). Conclusion Xiyanping treatment of hand, foot and mouth disease clinical efficacy, high safety, short course of treatment, no adverse reactions.