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目的:比较观察常用降压药物硝苯地平与依那普利治疗高血压的临床疗效。方法:纳入佛山市禅城区向阳医院收治的120例高血压患者作为研究对象,并将120例患者采用随机数字表法分为观察组和对照组,予以观察组患者钙拮抗剂类降压药物硝苯地平,予以对照组患者血管紧张素转换酶抑制剂类降压药物依那普利。结果:治疗前,两组患者血压状况、生活质量综合评定问卷(GQOLI-74)评分比较均无明显差异(P>0.05),治疗后观察组患者的血压状况优于对照组患者(P<0.05),GQOLI-74问卷评分,差异无统计学意义(P<0.05)。两组患者的药物不良反应发生率比较(P>0.05)。结论:钙拮抗剂类降压药物硝苯地平治疗高血压患者的临床效果优于血管紧张素转换酶抑制剂类降压药物依那普利。
Objective: To compare the clinical efficacy of commonly used antihypertensive drugs nifedipine and enalapril in the treatment of hypertension. Methods: A total of 120 hypertensive patients were enrolled in Xiangyang Hospital of Chancheng District, Foshan City. 120 patients were divided into observation group and control group by random number table. The patients in observation group were treated with calcium antagonist antihypertensive drugs Nifedipine, the control group patients with angiotensin-converting enzyme inhibitor antihypertensive drugs enalapril. Results: Before treatment, there was no significant difference between the two groups in the blood pressure status and the quality of life questionnaire (GQOLI-74) (P> 0.05). After treatment, the blood pressure of the observation group was better than that of the control group ), GQOLI-74 questionnaire score, the difference was not statistically significant (P <0.05). Two groups of patients with adverse drug reaction rates (P> 0.05). Conclusion: The clinical effect of calcium antagonist antihypertensive drug nifedipine in patients with hypertension is better than that of enalapril, an antihypertensive drug of angiotensin converting enzyme inhibitor.