论文部分内容阅读
在肾功能衰竭早期钙的代谢异常在肾衰早期(肾小球滤过率>30毫升/分),因为肾小球滤过率渐下降,肾对磷酸盐的排泄暂时减少,磷酸盐遂潴留,血中游离钙因之下降。后者促使甲状旁腺激素(PTH)分泌增多,于是肾小管重吸收磷酸盐减少,促使剩下的每一肾单位尿液中磷酸盐的排泄加多。俟肾排泄磷酸盐的总量增至等于饮食中磷酸盐的摄入时,血中磷酸盐降至正常。此时磷酸盐达到了
In the early stages of renal failure calcium metabolic abnormalities in early renal failure (glomerular filtration rate> 30 ml / min), because the glomerular filtration rate gradually decreased renal excretion of phosphate temporarily reduced, phosphate retention , The blood of free calcium decreased. The latter to promote parathyroid hormone (PTH) increased secretion, so the renal tubular reabsorption of phosphate reduction, prompting the rest of each renal unit phosphate excretion of urine more. The total amount of phosphate excretion in the kidney increases to equal the intake of phosphate in the diet and the level of phosphate in the blood is reduced to normal. Phosphate reached at this time