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目的 观察经门静脉化疗对肝脏恶性肿瘤的有效性和安全性。方法 在B超定位下 ,经皮经肝穿刺入门静脉分枝内 ,注入卡铂 5 0 0mg、5 氟尿嘧啶 10 0 0mg ,阿霉素 5 0mg或者榄香烯乳 40 0～ 6 0 0mg,治疗后临床观察 1～ 2个月。结果 观察治疗前后的临床症状、体征。行B超及CT检查 ,肿瘤近期疗效明显 ,临床症状改善 ,肿瘤均有不同程度缩小 ,平均缩小 2 1% ,3例门静脉内癌栓病人 2例癌栓消失 ,不良反应较轻 ,均能耐受。结论 B超定位下 ,经皮肝门静脉介入治疗肝癌可明显改善临床症状 ,缩小肿瘤 ,是一种有效的治疗方法。
Objective To observe the effectiveness and safety of portal vein chemotherapy for hepatic malignancies. Methods Under the B-ultrasonic positioning, percutaneous transhepatic portal vein grafts were injected with carboplatin 500 mg, 5 fluorouracil 100 mg, adriamycin 50 mg or elemene 400 000 mg, after treatment. Clinical observation 1 to 2 months. Results The clinical symptoms and signs before and after treatment were observed. B-ultrasonography and CT examination showed that the tumors had obvious curative effect in the short term, and the clinical symptoms improved. The tumors were reduced to different extents, and the average reduction was 21%. 3 cases of portal vein tumor thrombus patients disappeared in 2 cases with mild adverse reactions and were able to tolerate Accepted. Conclusion Under B-ultrasonography, percutaneous transhepatic portal vein interventional treatment of liver cancer can significantly improve clinical symptoms and reduce tumors, which is an effective treatment.