早在一世纪Celsus就已注意到并记载了烧伤瘢痕的癌变,1828年巴黎外科医生Marjolin首先报告1例在烧伤瘢痕上发生的癌变,由此而得名,Marjolin溃疡。烧伤瘢痕癌并不少见,Traves等报告1091例鳞状上皮癌中有2％源于烧伤瘢痕,特别是在肢体发生率更高。近年来随着烧伤局部治疗的改进,这一类瘢痕癌变也在逐渐减少中。自1988 Celsus had noticed and documented the carcinogenesis of burn scars in the early 1st century. In 1828, Paris surgeon Marjolin first reported a case of carcinogenesis on a burn scar, which resulted in the name Marjolin ulcer. Burn scar cancer is not uncommon. Traves et al reported that 2% of 1091 cases of squamous cell carcinoma originated from burn scars, especially in limbs. In recent years, with the improvement of local treatment of burns, this type of scar cancer has gradually decreased. Since 1988