本文分析1970年～1991年收治妊娠合并结缔组织疾病并足月分娩的19例临床资料,其中红斑狼疮9例(SLE7例,DLE2例),硬皮病5例,类风湿关节炎5例。本文中、重度妊高征达52.4％,2例硬皮病孕产妇死于重度妊高征的并发症一脑出血。2例死胎,2例新生儿死亡,6例小于孕龄儿。主要见于红斑狼疮及硬皮病患者。本文对结缔组织疾病与妊娠之相互影响及处理进行了讨论。 This article analyzes 19 cases of 19 cases of lupus erythematosus (7 cases of SLE, 2 cases of DLE), scleroderma and 5 cases of rheumatoid arthritis who were treated with gestational combined with connective tissue disease and full term delivery from 1970 to 1991. In this paper, 52.4% of patients with severe PIH, 2 cases of scleroderma maternal death in severe complications of pregnancy-induced complications of intracerebral hemorrhage. 2 cases of stillbirth, 2 neonatal deaths, 6 cases less than gestational age. Mainly seen in patients with lupus and scleroderma. This article discusses the interaction and treatment of connective tissue disease and pregnancy.